'''Riezene''' is a drug used by the Mechanical augmentation|mechanically augmented in ''Deus Ex: The Fall'' as a cheaper alternative to Neuropozyne. It helps prevent ''Neuroprosthesis'', a build-up of scar tissue that blocks electrical signals between augmentation electrodes and human tissue, ultimately resulting in rejection. It is manufactured by Zaaphire Biotech.

Unlike simple non-cybernetic implants, like a hip replacement which can be made from hypoallergenic materials, there is a need for any cybernetic augmentation that will "feel" and can be moved by the mind to have a neuroprosthetic junction, in essence a chip located within the brain to act as the interface between body and machine. Darrow Industries pioneered the PEDOT-cluster array design which was constructed to include both the organic conducting polymer electrodes and the neurons which would interface with the host's neurons, hence why it is called a "biochip".

The problem with implanting the biochip is that it causes glial tissue to build up around the junction, causing what is best described as nerve scars. The scarring eventually disrupts the integrity of the neuroprosthetic junction causing rejection syndrome also known as Darrow Deficiency Syndrome (DDS).

Riezene is a compound that prevents the buildup of glial nerve tissue around the junction. As of 2027 it is still in testing and not available to the public.